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Axial

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Sector Biotech
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Website Substack
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Tectonic Therapeutic: Protein Engineering and Fc-relaxin for Hypertension

Jan. 31, 2025, 1:16 a.m.

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Centessa Pharmaceuticals: Asset-Centric Business Model

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Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits

Jan. 31, 2025, 1:11 a.m.

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Real-Time Multistep Asymmetrical Disassembly of Nucleosomes and Chromatosomes Visualized by High-Speed Atomic Force Microscopy

Jan. 31, 2025, 1:10 a.m.

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Rapid proteome-wide prediction of lipid-interacting proteins through ligand-guided structural genomics

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The role of Claudin-1 in fibrotic disease

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Single molecule imaging of the central dogma reveals myosin-2A gene expression is regulated by contextual translational buffering

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DNA foundation modeling

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Functional protein mining with conformal guarantees

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Transannular C–H functionalization of cycloalkane carboxylic acids

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Alumis: Race to a Best-In-Class TYK2 Inhibitor

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Birth of protein folds and functions in the virome

Nov. 24, 2024, 4:13 a.m.

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Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics

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In vivo photoreceptor base editing ameliorates rhodopsin-E150K autosomal-recessive retinitis pigmentosa in mice

Nov. 23, 2024, 8:46 p.m.

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AnaptysBio: An Immunology Pipeline-In-A-Pill

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AbCellera: Going from Platform To Pipeline

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The Notebook of Leonardo da Vinci, The Codex Arundel

Oct. 22, 2024, 4:23 p.m.

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Groq's inference strategy

Oct. 22, 2024, 4:04 p.m.

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Eli Lilly acquiring Morphic Therapeutic timeline

Sept. 26, 2024, 7:15 p.m.

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Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution: Inventors & their inventions

Sept. 21, 2024, 6:01 p.m.

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Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli: Inventors & their inventions

Sept. 21, 2024, 5:54 p.m.

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Electrically driven proton transfer promotes Brønsted acid catalysis by orders of magnitude: Inventors & their inventions

Sept. 21, 2024, 5:46 p.m.

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LYMTACs: Chimeric Small Molecules Repurpose Lysosomal Membrane Proteins for Target Protein Relocalization and Degradation: Inventors & their inventions

Sept. 10, 2024, 10:43 p.m.

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Preclinical proof of principle for orally delivered Th17 antagonist miniproteins: Inventors & their inventions

Aug. 22, 2024, 6:02 p.m.

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A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα: Inventors & their inventions

Aug. 20, 2024, 3:38 p.m.

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